GUANIDINE HYDROCHLORIDE Tablets DESCRIPTION Chemically, guanidine (aminomethanamidine) hydrochloride is a crystalline powder freely soluble in water and alcohol The aqueous solution is neutral The structural formula is Each tablet contains 125 mg of guanidine hydrochloride with no color additive in the base It also contains the following inactive ingredients colloidal siliconGuanidine hydrochloride is used for purification of proteins and nucleic acids It can be used as a medicine, organic synthesis intermediate and is used in dyes It acts as an intermediate in the preparation of sulfadiazine, which is an important raw material for sulfamethyldiazine, sulfamethazine and folic acid It is utilized in the synthesis of 2aminopyrimidine, 2 amino 6Guanidine hydrochloride, 100 g ≥99,7 %, pa, protein Grade Write review Share Examples of effect Lead to damage to heath, cause irritation to eyes, skin or respiratory organs Are fatal in larger quantities Safety As previously stated, in the event of skin irritation or contact with eyes, rinse with water or a suitable medium Warning H302H332H315H319 i harmful if swallowed

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Guanidine hydrochloride protein denaturation
Guanidine hydrochloride protein denaturation-Guanidine HCL is a powerful protein denaturant SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren undAssay ≥ 98,0 % Water ≤ 0,3 % Downloads Technical Data Sheet Maciej Kuczynski T 49 8621 maciejkuczynski@alzchemcom Ask for a sample AlzChem Group AG



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Guanidine Hydrochloride material number and pack size Material Number Pack Size;・川口,尼崎倉庫の在庫は即日,その他の倉庫は2〜3営業日以内の出荷となります。 川口,尼崎倉庫からの配送対象エリア は各々異なります。 ・納期に関するご質問につきましては営業部までお問い合500 g Will be supplied as "Guanidinium Chloride, Solid" Unit of measure is "kg" Application Use Guanidine hydrochloride as a denaturing agent for proteins in a broad variety of nucleic acid purification applications Specification Formula CH 5 N 3 x HCl Molecular weight
Guanidine HCl, the crystalline compound of strong alkalinity formed by the oxidation of guanine, is a normal product of protein metabolism and a protein denaturant;Target Guanidine HCl is the most popular protein denaturant Analysis of unfolding transitions by Guanidine HCl provides several important parameters regarding the mechanism of conformational stability of proteins GuanidineGuanidine Hydrochloride Section 1 Identification 11 Product Identifiers Product Name Guanidine Hydrochloride CAS# RTECS# MF Synonyms Guanidine Monohydrochloride, Guanidinium Chloride, Guanidinium Hydrochloride 12 Recommended Use of the Chemical and restrictions of Use Chemical manufacturing 13 Supplier Details BioSpectra, Inc 100 MajesticGuanidine Hydrochloride textskipToContent textskipToNavigation TCI verwendet Cookies, um Ihre Benutzerfreundlichkeit zu personalisieren und zu verbessern Mit der Fortsetzung unserer Website akzeptieren Sie die Verwendung von Cookies Sie können die Einstellungen der Cookies jederzeit verändern oder aktualisieren Annehmen Published TCIMAIL newest issue No185
1000 · Chemically, guanidine (aminomethanamidine) hydrochloride is a crystalline powder freely soluble in water and alcohol The aqueous solution isGuanidine hydrochloride, the hydrochloride salt of guanidine, is commercially available It is a common chemical intermediate in manufacturing, as noted above It has been used to produce nitroguanidine, a component of rocket propellants Guanidine hydrochloride is also available as an orally administered human drug Its use is for the treatment of muscle weakness and easy fatigueGuanidine hydrochloride inhibits mammalian orthoreovirus growth by reversibly blocking the synthesis of doublestranded RNA Murray KE(1), Nibert ML Author information (1)Department of Microbiology and Molecular Genetics, Harvard Medical School, 0 Longwood Avenue, Boston, MA



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Guanidine Hydrochloride, technical grade is available with and without anticaking agent Notification EU US China Development Status Commercial Specification Substance Min / Max Unit;Guanidine Hydrochloride (GdnHCl) is a better denaturant than ureaIt should normally give higher and lower values for m and for Cm, respectively, but identical deltaG° values Since m values in both denaturants can be predicted/estimated from the size of the protein (Myers et al, 1995) and delatG° should not change, yes it is possiblein principleto predict Cm in one denaturant,Polyhexamethylene Guanidine Hydrochloride (PHMG) CAS No Molecular Formula (C 7 H 15 N 3) n x (HCl) Molecular Weight Structural Formula polyhexamethyleneguanidine Properties Polyhexamethylene guanidine hydrochloride is a kind of colorless or light yellow solid or liquid It is soluble in water and free of erosion PHMG biocide is environmental



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Guanidine exists protonated, as guanidinium, in solution at physiological pH Guanidinium chloride (also known as guanidine hydrochloride) has chaotropic properties and is used to denature proteins Guanidinium chloride is known to denature proteins with a linear relationship between concentration and free energy of unfoldingGuanidine Hydrochloride, Molecular Biology Grade CAS Calbiochem Powerful protein denaturant Find MSDS or SDS, a COA, data sheets and more informationGuanidine Hydrochloride is a powerful, chaotropic agent which is widely used for purification of proteins and nucleic acids, especially mRNA Guanidine Hydrochloride is useful for denaturation and refolding of proteins as well as in the recovery of periplasmic proteins and isolation of RNA


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Guanidinhydrochlorid (auch Guanidiniumchlorid) ist eine chemische Verbindung auf Basis des Guanidin, die als (chaotrope) Renaturierungs oder Denaturierungsmittel für Proteine in der Pharmazeutische Biotechnologie benutzt wird Weiterhin wird es als Zusatz für Flussmittel zum Löten eingesetztGuanidine hydrochloride (CDXG0040), CAS , is a high purity chemical used as powerful, chaotropic agent which is widely used for purification of proteins and nucleic acids It is useful for denaturation and refolding of proteins Purification of proteins and nucleic acids, refolding of denatured proteinsProtein digestion is an integral part of the "shotgun" proteomics approach and commonly requires overnight incubation prior to mass spectrometry analysis Quadruplicate "shotgun" proteomic analysis of whole yeast lysate demonstrated that GuanidineHydrochloride (GndHCl) protein digestion can be optimally completed within 30 min with endoprotease LysC No chemical



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Protein Denaturation Urea vs Guanidine Hydrochloride (GdnHCl) In equilibrium denaturation experiments, the concentration of urea at midpoint of denaturation is always higher than that ofFinden Sie eine große Auswahl an Organonitrogen compounds Produkten und erfahren Sie mehr über Guanidinhydrochlorid, 995 %, ohne Antikoagulationsmittel, ACROS Organics™Guanidine hydrochloride at low concentrations refolds acidunfolded apomyoglobin and cytochrome c, stabilizing the molten globule state, ie a compact denatured state with a significant amount of secondary structure, but substantially disordered tertiary structure Guanidine hydrochloride (> 1 M) causes cooperative unfolding of the molten globule state



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Description Purified Guanidine Hydrochloride LC7Grade, 60 % solution is used for » Downstream processing in biopharmaceutical manufacturing (eg isolation and extraction of monoclonal antibodies or recombinant proteins, column cleaning) » Diagnostics (extraction buffers for the isolation of nucleic acids from biological specimens, test kits for viral RNA/DNA in clinicalSummenformel CH6ClN3 MDLNummer MFCD Synonym guanidine hydrochloride, guanidinium chloride, guanidine, monohydrochloride, aminoformamidine hydrochlorideVirus inactivation of plasmaderived proteins by pasteurization in the presence of guanidine hydrochloride Transfusion 01 Mar;41(3)39 doi /jx Authors A Schlegel 1 , A Immelmann, C Kempf Affiliation 1 ZLB Bioplasma AG, Bern



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Guanidine hydrochloride is our Specialty chemical manufactured by Hebei Smart Chemicals Co,LtdGuanidine Hydrochloride is the hydrochloride salt form of guanidine, a strong basic compound with parasympathomimetic activity Guanidine hydrochloride enhances the release of acetylcholine following a nerve impulse and potentiates acetylcholine actions on muscarinic and nicotinic receptorsGuanidine hydrochloride (GuHCl) is a small hydroscopic molecule It plays a role in inhibiting heat shock protein 104 (Hsp104) adenosine triphosphatase (ATPase) activity in vivo It is a potent denaturant and inactivator of several enzymes and proteins



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塩化グアニジニウム(塩酸グアニジニウム、英: Guanidinium chloride )とは、グアニジンの塩酸塩。 GdmClやGndCl、GuHClと略されることがある。主にタンパク質変性剤として利用される。 · Guanidine Hydrochloride is a powerful, chaotropic agent which is widely used for purification of proteins and nucleic acids, especially mRNA Guanidine Hydrochloride is useful for denaturation and refolding of proteins as well as in the recovery of periplasmic proteins and isolation of RNA At higher concentrations, this strong denaturant has been reported to be ableOral Tablets 125 mg guanidine hydrochloride (Schering Canada for Key Pharm) /Guanidine hydrochloride/ Prescribing Information for Guanidine Hydrochloride, Key Pharmaceuticals, Inc Kenilworth, NJ USA;



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Guanidine Hydrochloride Product Code(s) Revision Date 08Aug11 MSDS M110 Target Organ Effects Bone marrow, Nerves Product Information Harmful if swallowed, inhaled, or absorbed through skin Causes skin, eye and respiratory tract irritation 10 STABILITY AND REACTIVITY Hazardous Polymerization Hazardous polymerization does not occurPrepare of 6 M guanidine hydrochloride by dissolving of guanidine hydrochloride into of dH 2 O Step 2 Once dissolved, complete the volume to with dH 2 OSubstance identity Substance identity The 'Substance identity' section is calculated from substance identification information from all ECHA databases The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas



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Thermo Scientific Pierce 8M GuanidineHCl Solution is an accurately formulated, readytouse solution of guanidine hydrochloride, that can be easily diluted and pHadjusted to any concentration below 8M Features of 8M GuanidineHCl Solution • Any concentration below 8M guanidine can be quickly and easily preparedGuanidine HCL is a chaotropic salt Chaotropic salts are critical for cell lysis and binding to the silica resin Specifically, Chaotropes have two important roles in nucleic acid extraction Destabilize hydrogen bonds, van der Waals forces and hydrophobic interactions Leading to destabilization of proteins (including nucleases)06 Available from, as of March 24, 08 http//dailymednlmnihgov/dailymed/drugInfocfm?id=1030



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Guanidine hydrochloride, PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production,Simagchem Corporation ist Lieferant für Polyhexamethylene guanidine hydrochloride Zusätzlich wird Propyl butyrate durch uns geliefert Ihr Partner in China für Chemiegeschäft szmtag Expertize in Lieferungen und Quellen von feinen, Spezialität, Pharmachemikalien und Zwischenprodukten kaufen Wir bieten qualitativ hochwertige Produkte und Dienstleistungen mit sofortiger JITThe activity and conformational change of human placental cystatin (HPC), a low molecular weight thiol proteinase inhibitor (12,500) has been investigated in presence of guanidine hydrochloride (GdnHCl) and urea The denaturation of HPC was followed by activity measurements, fluorescence spectroscopy and Circular Dichroism (CD) studies


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Applications of Guanidine Hydrochloride • Solubilizing proteins from inclusion bodies • Increasing solubility of hydrophobic peptides and proteins • Denaturing proteins Chaotropes, substances that disrupt the structure of water interactions, help to solubilize hydrophobic proteins and peptides for a variety of biological purposes For example, hydrophobic peptides and proteins may beGuanidin Hydrochlorid EC50 70,2 mg/l wirbellose Wasserlebewesen 48 h Guanidin Hydrochlorid ErC50 33,5 mg/l Alge 72 h 122 Prozess der Abbaubarkeit Es sind keine Daten verfügbar 123 Bioakkumulationspotenzial Es sind keine Daten verfügbar Bioakkumulationspotenzial von Bestandteilen der Mischung Stoffname CASNr BCF Log KOW BSB5/CSB Guanidin HydrochloridGuanidine hydrochloride 173M potassium acetate at 037M If I use this combination, the DNA does not bind to the membrane Instead, it ends up in



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